| 替诺福韦酯杂质列表（Tenofovir disoproxil Impurity-上海启太） | ||||||||||
| 序号 | 产品名 | 英文名 | 结构式 | CAS号 | 分子量 | |||||
| 1 | Me-POC PMPA |
Mono-POC Methyl Tenofovir Fumarate |
|
1246812-16-7 (free base) |
C15H24N5O7P. C4H4O4 417.36 116.07 |
|||||
| 2 |
MOC-POC PMPA (WHO-B) |
Mono-POC Tenofovir Fumarate |
|
1246812-43-0 (free base) |
C17H26N5O10P. C4H4O4 491.40 116.07 |
|||||
| 3 | DEC-POC PMPA |
Diethylamino carboxymethyl POC Tenofovir Fumarate |
|
NA |
C20H33N6O9P. C4H4O4 532.49 116.07 |
|||||
| 4 |
nPOC-POC PMPA （WHO-H） |
n-POC-POC Tenofovir Fumarate |
|
1217542-13-6 (freebase) |
C19H30N5O10P. C4H4O4 519.45 116.07 |
|||||
| 5 |
替诺福韦单吡呋酯 （WHO-A） |
Tenofovir Disoproxil Related Compound E |
|
211364-69-1 | C14H22N5O7P 403.33 | |||||
| 6 |
替诺福韦单吡呋 单乙氧基羰氧基甲酯 EOC-POC PMPA （USP、WHO-M） |
Tenofovir Disoproxil Impurity EOC-POCPMPA Fumarate |
|
1422284-17-0 |
C18H28N5O10P. C4H4O4 505.43 116.07 |
|||||
| 7 |
6-异丙氧甲酰胺 替诺福韦二吡呋酯 （WHO-E） |
Tenofovir Disoproxil Carbamate |
|
1244022-54-5 | C23H36N5O12P 605.54 | |||||
| 8 |
替诺福韦二吡呋酯 二聚体 （WHO-J） |
Tenofovir Disoproxil Dimer |
|
1093279-76-5 |
C39H60N10O20P2 1050.92 |
|||||
| 9 |
替诺福韦单吡呋酯 二聚体 (WHO-F） |
Mono-POC Dimer |
|
NA |
C29H44N10O14P2 818.67 |
|||||
| 10 |
替诺福韦酯 混合二聚体 （WHO-I） |
Mixed Dimer |
|
1093279-77-6 |
C34H52N10O17P2 934.79 |
|||||
| 11 |
替诺福韦酯 混合三聚体 |
IPC-Mixed Trimer |
|
NA |
C53H80N15O26P3 1436.22 |
|||||
| 12 |
替诺福韦酯杂质E （国际药典第7版） |
Tenofovir Disoproxil Impurity E (Mono-POC Tenofovir 6-Isopropyl Carbomate) |
|
1244022-56-7 | C18H28N5O9P 489.43 | |||||
| 13 |
替诺福韦酯杂质L （国际药典第7版） |
Dimethylamino carboxymethyl POC Tenofovir Fumarate |
|
NA | H29N6O9P. C4H4O4 504.44 116.07 | |||||
| 14 |
iPr-POC PMPA (WHO-D) |
Mono-POC Isopropyl Tenofovir |
|
1246812-40-7 |
C17H28N5O7P 445.41 |
|||||
| 15 | 去甲基替诺福韦酯 | Desmethyl Tenofovir disoproxil |
|
NA |
C18H28N5O10P 505.42 |
|||||
| 16 | N6-CH2OH-POC PMPA | Tenofovir Disoproxil Fumarate Impurity(N6-CH2OH-POC PMPA) |
|
NA |
C15H24N5O8P 433.36 |
|||||
| 17 |
替诺福韦酯杂质K WHO-K |
9-propenyl adenine |
|
4121-40-8 |
C8H9N5 175.20 |
|||||
| 18 |
替诺福韦酯 对映异构体 |
(S)-Tenofovir Disoproxil Fumarate |
|
1432630-26-6 |
C19H30N5O10P. C4H4O 519.45 116.07 |
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